PHARMACEUTICALS

Nabumetone Plant for GSK on their site in Irvine, UK. The project comprised of debottlenecking their existing plant and the detail engineering of new facilities of equipment for the expansion of manufacturing Nabumetone by hydrogenation using a semi continuous process. This comprised of reactors, hydrogenation facilities, vacuum systems, centrifuges, evaporators, pan dryers, relief systems and including packaging facilities.

Dista Products, Speke, Liverpool. A batch process detail design for manufacturing haemoglobin comprising of preparation of the raw materials, fermentation, centrifuging, homogenisation, chromatography, product slurry vessels, product blending, CIP, sanitization and sterilization facilities. The use of hot and cold purified water, clean steam and water for injections.

Basic process design for the manufacture of a cold influenza vaccine for Evans Medical, UK. Comprising incubators, centrifuge, ultra centrifugation, and CIP facilities.

Detail design, implementation and commissioning of a new lacquer and hair care products plant for Bristol Myers in Slough.

Process plant modifications for Yamanouchi, Ireland. Provision of the design for HCl gas safe receipt, bulk handling of containers, storage and distribution of the gas on site. Review of existing gas facilities (SO2 containers and Nitrogen bottles) with improvements. Review of their Nicarpidine dryer in a flammable atmosphere with detail engineering proposals for the immediate and safe implementation of charging, operation, and novel design features for complete emptying of the dryer under an inert atmosphere.

Process plant modifications for Schering Plough, Ireland. Provision and design of reliefs, inerting and rerouting and combining vents to a thermal oxidiser.

Relief systems for Astra Zeneca on their site at Macclesfield, UK. Review of their existing relief streams in the sterile and special products plants, tabletting facilities, development area, utilities and the boiler plant. Validating their relief design data and documentaions. Providing revisions and recommendations for improvements.

A case study for Roche, Dalry, UK for the improvements on their Butanol and Methylene Chloride distillation.

Design Study for Glaxo on emissions from their tank farms and prevention or minimisation using design modifications, absorption, adsorption and routing of vents to a thermal oxidiser

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